Simulated high-latitude soil thermal dynamics during the past 4 decades

High latitude hydrological changes during the Eocene Thermal Maximum 2

Improvement in survival during the past 4 decades among patients with anterior skull base cancer.

BACKGROUND The aims of this study were to determine the trends in survival of patients with anterior skull base cancer over several decades and to identify time-related changes in the demographic and clinical characteristics of this population. METHODS In all, 282 patients who underwent craniofacial resection at Memorial Sloan-Kettering Cancer Center and Tel Aviv Medical Center were studied. ...

Northern High-Latitude Climate Changes During the Holocene as Simulated by Circulation Models

To simulate the evolution of Holocene climate, forcing factors for the northern high-latitude climate are examined using different numerical models. A global coupled atmosphere–ocean circulation model driven by astronomical forcing over the last 7,000 years shows a long-term sea-surface temperature decrease in the Nordic Seas region associated with changes in seasonal insolation. A continuous c...

Advances in multiple myeloma therapy during two past decades

Multiple myeloma (MM) is a clonal B-cell malignancy characterized by aberrant expansion of plasma cells within bone marrow and extramedullary sites. It is one of the most common haematological malignancies; it accounts for 1.4% of all tumours and is responsible for 2% of cancer-related mortality. Over the last decades, the paradigm of MM therapy has changed dramatically - from the conventional ...

Micro Price Dynamics During Japan's Lost Decades

We study micro price dynamics and their macroeconomic implications using daily scanner data from 1988 to 2013. We provide five facts. First, posted prices in Japan are ten times as flexible as those in the U.S. scanner data. Second, regular prices are almost as flexible as those in the U.S. and Euro area. Third, the heterogeneity of frequency and size of price change across products is sizable ...